I Can See Health

  Chapter 325 Research that changes clinical guidelines?

   "Lu Chen, there is a male patient who needs to have a urinary catheter, please help me, in bed number 10."

   Gong Nannan walked into the doctor's office and said with a smile to Lu Chen.

   "Hey, it's coming soon."

  Lu Chen was writing the course of his illness when he heard Nurse Gong Nannan's words, he stood up and walked out of the office.

  Since Lu Chen came to the emergency department, many male patients have been handed over to him for the insertion of urinary catheters.

   Therefore, catheterization became one of the fastest skills for Lu Chen to reach 100% proficiency.

  Bed 10 is a young man in his twenties.

   "Don't be nervous, I'll be fine soon." Lu Chen came to the bedside of bed number 10.

   The young man looked green and embarrassed, and whispered, "Oh, be gentle."

   "Don't worry, take off your trousers first." Lu Chen put the catheter bag on the operating table by the bed.

   "Huh? This..." The young man's face turned red.

   "What are you afraid of, it's all big men." Lu Chen said sternly, "It will be over soon."

   "Oh." The young man took off his pants hesitantly.

   about a minute later.

   "Okay." Lu Chen smiled and said to the young man in front of him, "There's nothing uncomfortable."

  The young man nodded: "Thank you."

  Lu Chen wrapped the rest of the medical waste and threw it into the yellow medical waste bin.

   "Congratulations, +1 for the thank you from Maping!"

   Inserted a urine tube and got a little thank you.

  Lu Chen left the emergency ward satisfied.

  …

   "Hey, Lu Chen, I heard that we start the question earlier this year."

   As soon as he returned to the doctor's office, Cheng Peng came over.

   "When is it in advance?" Lu Chen was taken aback.

   He has been busy doing clinical research data recently, and he really didn't notice these things.

   Opening a topic refers to the direction of the subject and determines the research direction of the entire graduate student for three years.

   "Probably after New Year's Day." Cheng Peng thought about it.

   "After New Year's Day?" Lu Chen frowned.

   National ECG Contest, almost during New Year's Day.

   That is to say, when he finishes the competition and returns to school, it is almost time to start the question.

"It's not because a certain celebrity has an accident. They have a doctorate, and even CNKI doesn't know what it is." Cheng Peng pouted, "Now the Ministry of Education has stricter review of papers, before the repetition rate was only 20%. In our current class, it is actually less than 10%, which is too perverted! Therefore, in order to allow us to prepare the thesis earlier, the school has set the time for opening the topic earlier."

   Lu Chen also heard about this star.

   However, the quality of Huaxia's papers is really poor now, many of them are just one article, or after you have translated them into foreign languages, you can graduate.

   "Time is a little tight." Lu Chen thought to himself.

   The usual start time of the question is the start time of the second semester, but this year it was directly moved to the first semester.

  Lu Chen has some ideas about his clinical subject, but he still needs preliminary data support.

   He is now doing research for this early data.

   If even the data in the early stage is meaningless, then there is no need for him to continue.

   The most important thing now is that before the New Year's Day, the data in this early stage should be made quickly.

  …

  Eight districts in the heart.

Office of the Director.

  Lu Chen, Ke Yue, and Jiang Qingyan stood in front of the desk.

  Li Yao looked down at the opening report of the three.

   The corners of his mouth are sometimes raised, and his brows are sometimes wrinkled,

   for a long time.

Li Yao said slowly: "Well, Jiang Qingyan's idea is good, the toxic effect of anti-tumor drugs on cardiovascular, this research direction is very interesting. Foreign research in this field is very mature, but domestic research is still in its infancy. ."

"However, Ke Yue, your opening report..." Li Yao raised her head and glanced at Ke Yue, "How should I put it, the relationship between platelet aggregation and cardiovascular disease does not seem to be a problem, but have you turned to others? research literature?"

   Ke Yue lowered her head, "Look, I've seen..."

"Then you should also know that there are already many mature research and development achievements in your research field. If you do it again, although the entire research topic has no fatal problems, it is difficult to make something relatively new. In a word, it is like a chicken rib. , it is tasteless to eat, and it is a pity to abandon it.”

   "Yes." Ke Yue's voice was weak and flies, "Teacher, I'll go back and look for the literature."

  Li Yao nodded and said nothing more.

   Only Lu Chen's opening report was left, and Li Yao did not express any opinion.

  In the office, it is a little quiet.

  Li Yao's right index finger tapped the table lightly, making a small but regular sound.

After a long while, Li Yao looked up at Lu Chen.

   "The research on dapagliflozin to prevent early heart failure in patients with acute myocardial infarction, your research topic, did you think of it yourself?"

   Ke Yue and Jiang Qingyan looked at Lu Chen beside him.

  Is there any problem with this subject?

  Lu Chen nodded slightly.

   In fact, with the help of the system, he applied the clinical research skill card, combined with the current popular research field of cardiovascular medicine.

   Finally, I finally came up with this research topic.

"Very good, very good!" Li Yao said twice in a row, "Dapagliflozin is a relatively hot drug at present, and major laboratories around the world are researching it, and the research and development direction you have chosen is currently at home and abroad. It should be blank! If you can do it well and publish a high-scoring SCI, there is no problem.”

   "Even, if the sample size of the study is large, a large-sample, multi-center clinical study can be conducted to obtain the final R&D conclusion, which can even change the clinical treatment guidelines!"

   Change clinical guidelines?

   Everyone present, including Lu Chen, all showed expressions of astonishment.

  Lu Chen originally just wanted to publish an SCI paper, but he did not expect Li Yao to give such a high evaluation.

   Ke Yue and Jiang Qingyan looked at Lu Chen in disbelief.

   No one could have imagined that the opening report made by a graduate student might change the clinical guidelines!

Li Yao continued: "Don't be so surprised, you need to know. Dapagliflozin has just been listed as a routine drug for the treatment of heart failure, and the medical field has recognized its status, but in the current clinical practice, it is not in acute Research on myocardial infarction, so it's not included in it."

"but…"

Li Yao changed her words and stared at Lu Chen: "Everyone knows that clinical research is not a method! It requires a lot of manpower, material and financial resources! The sample size you wrote in your opening report is only five Ten people, this kind of sample size, at most one low-scoring SCI paper. If you want to change the clinical guidelines, then the amount is at least tens of thousands! Generally, this kind of research on changing the clinical guidelines is based on the leading hospitals in the country. Leading the major tertiary hospitals, the sample size is very large, such research results are suitable for clinical use."

  Lu Chen nodded, he understood what Li Yao meant.

  Clinical research, good ideas are important, but they also require a lot of financial and material resources.

   In a prospective study, only a sample of fifty people is definitely not enough, and it can even be said that there are very few, very few!

   But with a sample size of fifty people, the funds that need to be spent are already tens of thousands, or even more.

   This is also the limit that Lu Chen can bear at present.

   It is not realistic for Lu Chen to spend more money on clinical research!

   "Let's do it." Li Yao continued, "Lu Chen, you should start with a sample size of 50 people. If the previous experimental research is meaningful, then consider whether there is any further possibility."

   "Good teacher." Lu Chen smiled.

"Actually, the sample size of these 50 people costs a lot of money." Li Yao said solemnly, "I will give you some subsidies in the name of the laboratory. Secondly, when you collect data, I will let you know The medical staff in the inner eight districts will cooperate with you."

   The so-called prospective study requires patients to return to the hospital for re-examination in a timely manner, which involves examination fees, round-trip travel expenses, etc.

   "Thank you, teacher!" Lu Chen looked overjoyed.

   His biggest resistance now is not actually money, but to do a good job in clinical experiments, the medical and nursing cooperation of the department must be required, otherwise it will be difficult to collect first-hand data.

   Now, with Li Yao's sword, Lu Chen's future clinical research should be much easier.

   "By the way, both of you are too." Li Yao said to Ke Yue and Jiang Qingyan, "I will let the nurses in Corey cooperate with you."

   "Thank you teacher." Ke Yue and Jiang Qingyan said in unison.

When    walked out of the director's office, all three of Lu Chen's faces showed happy expressions.

   As a mentor, Li Yao is already quite responsible for doing this.

  Many graduate tutors basically let students fend for themselves.

   Some tutors even impose some unreliable research on students.

  …

   Seeing the backs of the three of them leaving the office, Li Yao was very relieved.

   The quality of the students this year is too high.

   The clinical research topics of Lu Chen and Jiang Qingyan are very innovative and should be able to produce good results.

   Ke Yu's subject was a little worse, but he was good enough for graduation.

   Li Yao, a student of the previous two years, did not offer such a convenient condition.

   It can be seen from the body of Senior Sister Wang Shasha.

   "I hope the three of them don't let me down."

  Li Yao looked at the three opening reports in front of her with a smile in her mouth.

  …

   Leaving the doctor's office, the three of Lu Chen walked down the path of the hospital.

   "Lu Chen, you are amazing, the teacher said that your subject can even change the clinical guidelines!" Ke Yue couldn't help giving Lu Chen a thumbs up.

   "That's a large sample size. I only have fifty samples now. It's enough to send an SCI." Lu Chen smiled.

   It’s not that he is humble, it’s the sample size that determines it.

   "Oh, it's already amazing!" Ke Yue laughed.

   At the same time, she was also happy.

   It seems that helping Lu Chen record data is a very correct choice!

  If Lu Chen posted an SCI and could bring her name, it would make a lot of money.

   "Jiang Qingyan's topic is also good." Lu Chen smiled, "Ke Yue, you have to revise your topic report properly."

   Jiang Qingyan smiled.

   Ke Yue pouted, "Hey, I see, it seems that I have to stay up late again..."

   The three of them chatted all the way, and separated in front of Guipeikou's dormitory.

  …

   Back to the bedroom, everyone in the bedroom was discussing the topic.

   "The data for the early stage of my project is almost ready." Wang Zihao patted Lu Chen on the shoulder, "Thank you to Lu Chen! Without you, I wouldn't have been so fast."

   "Hey, I don't even have any ideas, I'm about to start the question, it's really difficult!"

   Another roommate, Xing Yu, frowned.

   "Brother Yu, go ask your boss! Doesn't he have any subjects?" Wang Zihao wondered, "Just let you do a sub subject, it should be enough for you to graduate, right?"

"Hey, I asked." Xing Yu gave a wry smile, "My boss asked me to think for myself, and then let him change it. As for his subject, I don't think he can figure it out himself, he is looking for outsourced experiments. I want him to give me a sub-project, don't even think about it."

   "Uh... It's really hard for you to meet an unreliable boss." Wang Zihao shook his head slightly, then looked at Lu Chen who was beside him, "Lu Chen, have you done your clinical project?"

   "The opening report has been written, but the preliminary data has not yet been completed." Lu Chen shook his head.

   "Then hurry up." Wang Zihao said, "I remember you have to go to Bingcheng to participate in the electrocardiogram competition, right? When you come back from Bingcheng, we almost have to start the question."

   "Yeah." Lu Chen nodded, "I asked two classmates for help, and I should be able to complete the preliminary data."

   "That's good." Wang Zihao said.

   Everyone in the bedroom chatted for a while.

   Wang Zihao suddenly received a WeChat message. After reading it, he said, "Lu Chen, my sister wants to invite you to dinner again."

  Lu Chen was processing the data of clinical research. Hearing this, he was stunned.

   "Didn't you eat it some time ago? Why did you eat it again?"

   "Last time was a thank you banquet, this time she is going to come to the hospital for a follow-up consultation." Wang Zihao said, "So I want to make an appointment with you in advance to get some information from you."

   "This...isn't necessary." Lu Chen said, "Your sister will come for a follow-up consultation and send her to the cardiology outpatient clinic. I can't prescribe medicine or do any tests here."

   "I told her this, but she still wants to come to you." Wang Zihao said, "Lu Chen, you should go and have a free meal. Anyway, it's only one morning. So that my sister won't bother me again."

  Lu Chen thought for a while and said, "When?"

   "Tomorrow is the weekend, just tomorrow, at 11:30 noon, at the Shangri-La Hotel."

   "Shangri-La...isn't it cheap?" Lu Chen laughed.

   "Don't worry, my sister is a rich woman." Wang Zihao smiled, "If you eat a few more meals, you won't be able to eat her."

   At this time, Xing Yu whispered from the side: "Zihao, I also want to rub for a meal, I don't want to work hard..."

   "Go away, go to the side." Wang Zihao scolded with a smile, then looked at Lu Chen, "How is it, go or not?"

Lu Chen nodded: "You said so, I'm definitely going. However, can we change the place? It's just at the restaurant in front of our hospital. It tastes good and the price is affordable. I have to process the data tomorrow afternoon. Besides, , going to a high-end western restaurant like Shangri-La is too restrictive, and the appetite is not much better."

   "This should be no problem, I'll contact my sister." Wang Zihao laughed.

  …

   (end of this chapter)