Plague Doctor

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Hoo, the examination bed moved to the ring magnet, Gu Jun motionless, relaxed his mind, didn’t want anything, let the device photograph his control state first.

While the FMRI machine is running, it is located in front of the operating table in the front room. Professor Ma, Court Academecian and the others are all looking at the video pictures on several computer screens.

At this time, the blood flow of Gu Jun’s brain is displayed in the image, but only professionals can understand what the different colors and color brightness of the different brain regions mean, and the parameters such as MR value, TE value, T2 value, etc. Information disclosed.

Not to mention Wu Shiyu, Cai Zixuan can only hope to sigh.

“Ajun this state is normal.” Shen Court Academecian said to them.

After a while, after inputting enough control state image data, Professor Ma said to Gu Jun through the horn of the examination room: “A Jun, I will do the stimulation task from light to heavy. First, I will talk about the abnormalities. You listen carefully. If you feel a headache, do n’t hold it. Let us know how important your situation is with a cry. If you ca n’t stand it, must tell me to stop immediately. ”

“Okay.” Gu Jun in the examination room answered, “Professor Ma, let’s get started.”

Professor Ma’s middle-aged face, Yan Zhenyi slowly began to say one by one Name: “Curses, deep dives, isoscus disease, human isoscus …”

With Professor Ma’s words, the color brightness of the brain image on the screen suddenly increased, and the neuron activity in Gu Jun’s brain became more active.

“Different disease, ceremony, Dagon, Tian Yiqing …” The more Professor Ma said, the brighter the color of the image, and the more nervous everyone was.

“Ah!” Gu Jun suddenly uttered a cry of pain, and he felt that his head changed from hidden pain to bursts of severe pain, which had made his body a little stiff.

This is his stress state and the task state of this inspection. By subtracting the blood flow chart of the control state from the blood flow chart of the task state, the computer may find the brain part related to the specific psychological operation in the task state, and now a screen displays the instant comparison results.

Shen Court Academecian naturally understands the image, frowning at the next look and whispering to Wu Shiyu: “The blood flow in these three places has increased significantly in the frontal lobe, amygdala, and hippocampus.”

Cai Zixuan couldn’t help but sigh, grabbed his bald forehead, these three places are not good …

He has seen some PTSD research literature. One of the main research results of PTSD brain imaging is that the patient ’s hippocampus and the hippocampus gyrus, amygdala, prefrontal lobes and other functions are abnormal, so there is “prefrontal-amygdala- “Hippocampus Loop” pathological hypothesis.

That is, damage to the prefrontal lobe leads to weakened function, thereby weakening the regulation and control of the amygdala, which makes the amygdala excessively enhance the response to terror, and the damage of the hippocampus itself and the imbalance of the connection between the prefrontal and amygdala also participate The process of damage to the patient’s memory.

The results of Hao Jun’s blood flow changes are in line with this hypothetical typical performance of local brain activity.

The location of Haojun’s brain hemorrhage was the right prefrontal lobe. If the injury and related surgery caused the abnormal function of the prefrontal lobe, then the cause was found.

“Ajun, now increase the excitement, you think about what happened on that island.” Professor Ma said again, “stop once you can’t stand it, don’t force it.”

Gu Jun complied with this stimulating task, and his head hurt so much that he couldn’t bear it anymore, and his breath changed into a gasp.

Then came the most important task. The nurse next to the FMRI machine gave him a document with pictures of abnormal things such as the body of the deep-diver and the patient with isospermia. Gu Jun had only seen 2 or 3 pictures, and his head was so painful that he showed signs of involuntary muscle twitching before the seizure. He closed his eyes and stopped.

And the stimulation task of this examination is over, but Gu Jun does not leave the examination bed for the time being, letting the machine continue to record the changes of cerebral blood flow during his recovery process.

On the other side, Professor Ma and Court Academecian Shen looked at the contrasting images in the computer, and their faces became more ugly and a bit surprised …

When Gu Jun recalled the traumatic scene, the blood flow continued to increase; and when he watched the stress picture, he experienced drastic hemodynamic changes, not just the three brain regions of the prefrontal lobe, amygdala, and hippocampus, but The blood flow of the whole brain has increased sharply, and this physiological response is much stronger than that of ordinary PTSD patients under stress.

Moreover, such rapid whole brain congestion is very dangerous and will cause a sudden increase in blood pressure, which can easily cause micro blood vessels in the brain to rupture and cause bleeding.

Considering Gu Jun’s history of cerebral hemorrhage and craniotomy, this level of stress is fatal to him.

“Not optimistic, really not optimistic …” Shen Court Academecian muttered, not a pessimistic person, but felt helpless at this time.

After Gu Jun came out of the examination room, as soon as he saw their expressions, he knew that the situation was not optimistic.

When he looked at the results of the images, he was a little confused. Was the function of the frontal lobe damaged abnormal, which is difficult to cure …

“Xianjun.” Wu Shiyu pats his shoulders, “You were comatose before big half a month, it will get better slowly.”

“En.” Gu Jun nodded to her and said to Professor Ma: “Professor Ma, I would like to do the MRI and MRS as well. Check it out.”

MRI is nuclear magnetic resonance, which belongs to brain morphometry when used in brain function tests, and MRS belongs to in vivo magnetic resonance spectroscopy. It can measure the volume of the hippocampus and assess whether hippocampal neurons are lost or damaged. Because structural changes in the hippocampus are typical symptoms of PTSD patients.

Doing these two kinds of examinations requires radioactive substances, that is, contrast agents, which were not easily used due to concerns about the side use of his body.

Now that it is both Gu Jun’s request and BOLD-FMRI cannot indicate the structure of its hippocampus, Professor Ma and Court Academecian Shen agreed to carry out an inspection, but let Gu Jun rest in the laboratory for 3 hours. Then the nurse gave him contrast medium, and then he completed the MRI and MRS examinations.

MRI is a Dissection image, and MRS is the synthesis of all chemical signals recorded in the measured individual. The measurement result is a spectrum of multiple spectral lines.

On Gu Jun’s MRI images, there are indirect signs of hippocampal volume reduction-his lateral ventricle temporal angle is enlarged, and the superficial groove of the hippocampus disappears.

The MRS results also showed that his hippocampal neurons had a reduced signal.

On this day, Gu Jun also did some other tests, such as blood test to measure the level of BDNF (brain-derived neurotrophic factor). The BDNF level of patients with PTSD is usually lower than that of the normal population. Now his BDNF level is on the low side, and it has fallen sharply compared with the result of the last medical examination.

There are research data from the Tianji Bureau that the BDNF level of highly psychic people will be higher than that of normal people, which may also be the source of their psychic knowledge.

Now Gu Jun seems not only to lose his high spiritual knowledge, but also has the neuroendocrine characteristics of PTSD pathology.

All these examination results are put together, and Professor Ma knows the answer … Gu Jun’s brain morphology has indeed changed.

“Ajun, you go back and have a good rest and relax, don’t think so much, we will discuss a treatment plan that is most suitable for you.” Shen Court Academecian pretended to comfortably and sent Gu Jun 3 out of the laboratory.

Then, Shen Court Academecian and Professor Ma came to the Conference Hall beside to have a remote conference. Tong Ye, Yao Shinian, and the director and the others were all waiting for the inspection report.