Rebirth of the God-level Xueba

Chapter 139: R&D chain

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   Yao Yue, who put on light makeup, made hibiscus in water, and his sweet and fresh smile gave Yang Rui a slight sense of surprise.

  

   Yang Rui has always been unable to tell whether a woman wears makeup or not. Except for heavy nightclub-style makeup, he, like most men, doesn’t look into the details of a woman’s face. He knows whether it looks good or not. That’s why girls have the meaning of makeup.

  

   However, girls in the 1980s obviously didn't understand this. In the first two years, "Iron Lady" was being promoted everywhere in the country. The so-called "Use women as men and men as cattle" was definitely a word of praise before the 1980s. The literati often wrote "Who Mulan-style reportage that says women are inferior to men.

  

With the reform and opening up, women’s aesthetics began to awaken. Handmade sweaters, shirts, red skirts, bell-bottoms, and flared trousers gradually appeared, but there were still very few people who put on makeup, especially in prefectures and counties. I have put on makeup, and when I get married, I put on some blush, which is already a heavy makeup.

  

  Yao Yue is a girl from a big city. Despite her simple conditions, she is young and invincible after all. With a careful dressing, she can easily highlight her bright and charming girl image.

  

   For Yang Rui, who hasn't watched TV movies for a long time, and even fashion posters have not seen for months, the impact of the live-action 3D beautiful girl is far better than the 2D animated beautiful girl.

  

   What is even more unbearable than Yang Rui is He Cheng as an experimental assistant.

  

   He Cheng, who grew up in a township, only has space for activities around Xibao Town. His only chance to see beautiful women is through movies.

  

   However, the hazy township film film, how can it be compared with the living beauties.

  

   He Cheng glanced at the calf under Yao Yue's long skirt, and he had the urge to spray a nosebleed. The experiment he was doing on his hands was completely messed up.

  

   "Pretty!" Yang Rui complimented naturally.

  

   In terms of appearance, he is still somewhat confident.

  

   It was Yao Yue who blushed first. He lowered his head slightly and said: "Yesterday's clothes were dirty."

  

   answered a bit inexplicably, I don't know what it was explaining.

  

   Actually, it is Yao Yue who feels that what she wears is a bit too ostentatious.

  

   The red one-piece skirt under the white coat is as dazzling as a catwalk in a world of green military uniforms and gray cloth clothes.

  

   As far as the sense of the times is concerned, it is equivalent to a certain star walking in the Wulipu of Tangjiabao in a dress that was worn when shopping on the Avenue des Fragrance in Paris.

  

   But Yao Yue is also telling the truth. When Yao Yue came to Xibao Town, he also brought such a change of clothes. As for why he brought his most beautiful clothes from Shanghai *hai, this kind of little girl's mood is not worth mentioning.

  

   Yang Rui thought it was very good-looking, in line with his own aesthetics, and he looked around her naturally, and smiled: "What should I do? Wearing a white coat outside is wasted, and if you don't wear a white coat, you can easily get dirty."

  

   "When my clothes are dry, I will change them back." Yao Yue obviously has not received such direct compliments, and he is more shy when he is delighted.

  

   Lu Zhi gently pushed him with his elbow, and said, "What do you do when you change back, you don't stay in the laboratory all day, you still have to wear your own clothes when you go out."

  

   "Don't talk about clothes, what are you doing in the experiment? Can I help?" Yao Yue continued with embarrassment.

  

   Yang Rui also has no experience in love, and he failed to seize the opportunity to chase, and his thinking was biased. He said: "We are doing verification experiments to test the authenticity of several Japanese papers."

  

   Yao Yue saw what he said about the experiment, and immediately felt relieved. Seeing He Cheng’s preparation for the experiment, he picked it up and looked at it, and said, “Is it the plant extraction you told me about?”

  

"Yes, Japan is a small country and the animal husbandry industry has always had little competitiveness. Therefore, their scientific circles have always disliked tissue extraction methods. For the sake of interest, pharmaceutical companies have been developing tissue extraction methods while actively experimenting with plant extraction and microbial cultivation. There has been some progress in both the method and the chemical synthesis method." Yang Rui gave a general explanation. In the field of biopharmaceuticals, Japan has seized the opportunity and is developing very fast. Certain biological products, such as insulin, are occupying the global market. The same is true for coenzyme Q10. Japan was the first to make efforts in this field, and at the same time tried plant extraction, microbial culture and chemical synthesis. In the 1980s, it selected a semi-plant extraction and semi-chemical synthesis method, and gradually promoted microbial culture in the 1990s. France, the money spent is gold and silver. In this regard, China in the 1980s could not even afford admission tickets.

  

   However, the cost of biopharmaceuticals lies in research and development. For Yang Rui, who already has the answer, it is not that expensive to replicate once successfully.

  

Of course, it is relatively inexpensive. His laboratory spent more than 30,000 US dollars, plus 20,000 US dollars in cash. This time all invested in it, that is, one or two attempts. If it fails, Many inputs cannot be recovered.

  

This is the last train of Yang Rui’s luck to catch up with the plant extraction method. If it is the microbial cultivation method, there is no need to try it. A good fermentation tank can sell for tens of thousands of dollars, and a string of fermentation tanks can cost hundreds of thousands of dollars. Yang Rui received this year's dividend, but it was not enough to make a copy.

  

   As for the pure chemical synthesis method that should be the most advanced and the lowest cost, until 2014, there was no mature industrial production method. The large international pharmaceutical companies invested tens of millions of dollars for this, which is an invisible bottomless pit.

  

  Yao Yue and the others have begun to enter the laboratory to help, but they don’t know the research and development itself. After watching for a while, Yao Yue asked curiously: "Is there any results in Japan? Are we going to do research on localization?"

  

  Yang Rui was surprised: "Why do we have to copy it because Japan must have achieved results?"

  

   "Localization and copying are not the same." Yao Yue anxiously: "It is to fill the domestic gap and save foreign exchange for the country..."

  

"That's not plagiarism. Research on localization is the most time-consuming project, and this is not military equipment." Yang Rui said in his heart: I just plagiarize, and I will not copy the patented technology. I will do repeated research. What do you mean.

  

   Lu Zhi also turned his head to look at the preparations for the experiment. She didn't know exactly what experiment Yang Rui was going to do, and asked: "Do you want to conduct experiments based on Japanese research? It's more difficult."

  

  In the hearts of Chinese people, foreign research is naturally advanced, and doing research on a foreign basis is naturally extremely difficult.

  

   There is actually no error.

  

Experimental science is done by relying on experimental equipment. Experimental science without experimental equipment is rootless. Perhaps, occasionally, there will be one or two bright ideas to replace repeated machinery and equipment. However, it has to be for a lifetime. People like this should not engage in experimental science but should sing little stars.

  

  Foreign laboratories are equipped with advanced equipment, and the scope of their research is wide. If you want to do research on the basis of them in China, it is better to have more advanced equipment, but at worst, you have to have similar equipment.

  

This is like the goalkeeper Leeuwenhoek, a Dutch without formal education. When he grinds out an excellent lens and sees the world of microorganisms, even his article "Leavenhoek uses a homemade microscope to observe the skin "Some records of meat, bees, and other insects" are so rough that scientists from the Royal Society had to publish it in the journal of the Royal Society after verifying the paper with the help of Leeuwenhoek's microscope. .

  

   No matter how clever other people are, no matter how nice they are to sing the little stars, without a microscope with a magnification of two or three hundred, he is not qualified to do research on the basis of Leeuwenhoek.

  

   The development of modern industry has made the threshold of science higher, rather than lowered. To catch up with the footsteps of developed countries, for the Chinese in the 1980s, it was a hard work that could hardly even see hope.

  

   If Lu Zhi worked in a university laboratory for three or four years, he would definitely not ask such questions.

  

However, Yang Rui’s answer is yes: “We have to avoid the technical barriers of Japanese pharmaceutical companies. Well, there are no barriers that can be called barriers. They are just stumbling blocks. No matter what, we must use our own methods to accomplish this. Certain basic researches are the basis for plant extraction methods, and then, on this basis, we have to establish our own technical barriers for plant extraction methods. The work is very arduous and there are few researchers. So, let’s do it now. let's start."

  

   Yang Rui said, he set up a task~www.NovelMTL.com~ If it is a large pharmaceutical company in Europe and America, it would not do this. They will first use the research results of a Japanese pharmaceutical company, regardless of whether it has a technology patent, and then, after a profitable technology is born on the basis of this patent, they will look for a solution in reverse, and it is naturally good to find a solution. Make money happily. If you really can't find a solution, you will blatantly infringe and wait for the other party to sue, and send dozens of lawyers to accompany the other party in litigation every day, and at the same time sell drugs happily.

  

  Small and medium-sized pharmaceutical companies are afraid of such large vultures. Because this kind of patent lawsuits usually last for a few years. A group of lawyers with dozens of hundreds of people may spend tens of millions of dollars a year. Small and medium-sized pharmaceutical companies will go bankrupt before a court verdict, and only large pharmaceutical companies. Just can afford it.

  

Yang Rui is not a pure researcher. He wants to make money from this technology. He has only an ultra-small biological R&D team. He must first solve the other party’s technology patents, then establish his own technology patents, and then take all the patents at a price. .

  

   And all these steps and processes require experiments and papers to support.

  

   There is no process, just get a result. Except for those super-large giants, the drug administration of any country will not ignore it. Pharmaceutical companies will not bid well.

  

   Even if it is only a difference in extraction method, a strict R&D chain must be established.

  

   This is a huge test for Yang Rui, who is seriously underfunded. He can only comfort himself. Fortunately, it is the meta-era of biotechnology.

  

  ……◇ (to be continued)

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