Rebirth of the God-level Xueba

Yang Rui drove the car and drove from Shichahai to the laboratory, that is, twenty to thirty minutes, the capital without traffic jams, the young people in the future will probably be... well, you can feel it during the Spring Festival.

The researchers in the laboratory did not have the relaxed mentality of Yang Rui.

Wang Liangcai, Su Fan, Gu Qiang, Tian Bing, and many of the assistant researchers who were transferred were all a little uneasy, either with a solemn expression, a solemn expression, or a heavy weight...

Judging from the experimental results, they felt that they had made breakthrough progress, and they had already carried out repeated experiments to verify-pulling the lab boss back from the bed so late, they had to make sure and then make sure.

The reason why there are so many people is to convene people to carry out repeated experiments for verification.

Of course, the main reason is that everyone did not get off work.

The food in the laboratory is good and the food is good. The chef will help you make supper if you stay late. You can also pack the leftovers and pay for overtime. Who will go home if it’s okay?

Besides, what can the experimental dog do after get off work? Do you want to chat with your wife?

Just kidding, can an experimental dog have a wife?

Does the wife of the experimental dog like to chat? If she likes to chat, why marry a taciturn experimental dog?

All of the above illustrates one point.

A group of extremely boring guys, although they have spent many hours in the laboratory, they still can't be sure that they have really made a breakthrough.

The project they are working on is "cloning", and it is the cloning of mammals.

Such a project may produce dozens of top-level papers casually. It is no exaggeration to say that if the project of cloning sheep focuses on publishing papers, from "Cell" to "Nature" to "Science", half of the space has to be freed up for preparation.

In other words, if the immediate results are confirmed, the research team has booked at least one S.

"Wang Liangcai, did your team complete it? What is the situation, just say it." Yang Rui glanced in the door, hung up his coat, and talked as he walked.

Wang Liangcai coughed a little nervously and said, "Yes, we have completed the nucleus injection process. At present, the cells after the nucleus injection have met the requirements. Some indicators have exceeded expectations."

"Our team also completed a nuclear injection." Gu Qiang was stuck in time and inserted: "Moreover, our team completed a little earlier than Wang Liangcai's team."

Yang Rui turned his head and glanced at Gu Qiang, and asked, "Why didn't you call me? Lost the number?"

"How can I do it, I have memorized it." Gu Qiang said in a low voice, and said: "We want to repeat the experiment and call you again."

"Are you ready?" Yang Rui asked.

"Yes...not yet." Gu Qiang replied helplessly. It is not the first time that his team has completed the nuclear injection step. In fact, the nuclear injection was originally completed by his team.

However, it is difficult to overcome difficulties, and experience is rare.

Continuously completing the nucleus injection does not mean that they can get the nucleus-injected egg cells that meet the requirements. Even if they get the nucleus-injected egg cells that meet the requirements, it does not mean that they can repeat it smoothly.

It is difficult to repeat the experiment, which is a big trouble for Gu Qiang's group.

He always relies on luck to overcome difficulties again and again.

However, repeating the experiment can't just do it by yourself, it has to be done by others.

Only in this way can we get help and ensure a stable supply of nucleus-infused oocytes.

To complete the cloned sheep, a huge amount of nucleated egg cells is needed.

Yang Rui’s plan is to prepare 1,000 copies of nucleus-infused oocytes. Historically, the Scots used about 550 qualified oocytes to obtain a cloned sheep, Dolly, the only cloned sheep. The process of pregnancy. It was quite dangerous, but several sheep companions were lost in the circle.

Nowadays, Yang Rui has carried out the sheep cloning project several years in advance, and the domestic conditions are weaker than those in the United Kingdom. Taking care of ewes is a technical job in itself, and the tortured oocytes have various congenital deficiencies...

Therefore, when Gu Qiang's experimental group cannot stably carry out repeated experiments, it is not enough to obtain only one undamaged nuclear-injected cell, even if it is a nuclear-injected cell that reaches the target.

Yang Rui can guess that there is a problem with Gu Qiang's group without asking carefully.

However, he rushed over today, not to be a confidant brother to Gu Qiang.

Yang Rui just nodded slightly, turned to Wang Liangcai, and said, "Give me the experimental record, let's start talking."

Yang Rui stretched out his hand and got the record, turning his finger while looking at it, indicating that Wang Liangcai would proceed simultaneously.

Wang Liangcai took a deep breath and said, "We have improved the method of denuclearization."

"Oh? Second improvement? Not bad." Yang Rui's attention was instantly attracted.

The method he gave was already very advanced, which made him want to hear about Wang Liangcai's improvement method.

"I'm talking about the main part." Wang Liangcai said: "We used the spindle to jam the nucleating needle, and then **** the fragmented nuclei."

"Yes."

"The improved method still uses the tougher characteristics of the spindle, but we **** in a part of the spindle directly."

"Oh?"

"The advantage of this is that it is possible to completely **** the nucleus, less pollution, and faster." Wang Liangcai paused and said: "Although the success rate has also been lowered, I think it is worth it."

Of course it is worth it. Yang Rui admired Wang Liangcai's experimental talents, and even had some...a little jealousy.

The so-called experimental genius is like this.

In order not to be too advanced, Yang Rui did not actually give the most perfect solution, but just gave the basic version of the solution, simply using the spindle to make a fuss.

Who would have thought that Wang Liang had just learned the basics and advanced by himself.

This kind of acuity and execution is truly breathtaking.

Yang Rui had originally planned that when it came time to carry out large-scale nuclear cell injection, he would explain the improvement of the test method-it was only the experimental stage, which would not take much time, and had the benefit of gradual practice.

Who could think that Wang Liangcai solved the mystery just like that.

Yang Rui nodded helplessly and agreed, and said, "The idea is very creative, what's the result?"

"Comparative experiments prove that it is significant." Significance refers to the data. Wang Liangcai omitted it at this time. To a layman, it seems to be a bit silly, but in the laboratory there is no violation.

The experimental results are naturally significant. Yang Rui smiled to himself, turned to the part of the experiment record, and checked it.

Although it was an expected result, he still needs to verify it carefully.

Academic fraud occurs in the details, no one will modify the final number and make the results match. Of course, there are always idiots, but they are not significant.

The normal academic falsification pattern starts with the original data, changes the original number, and then uses the normal calculation icon to make the following numbers, which seems pretty serious.

In the responsibilities of the project leader or laboratory director, the most important point is to suppress the impulse of fraud by other scholars in the laboratory, and at the same time, bear all the consequences of academic fraud.

Therefore, after the Japanese beauty researcher was still arguing after making a fake, her mentor committed suicide.

At this point, the project leader is a bit like a chef in a western kitchen. He doesn't need to do it himself, but he has to check everyone's work and do the final quality control work.

Wang Liangcai had confidence in the experimental record, and was not worried about it. After Yang Rui watched it for a while, he continued: "The denuclearization part is only a minor modification, not the main breakthrough."

"I have stronger confidence in your team." Yang Rui couldn't help showing a smile on his face, which made the other researchers breathe a sigh of relief.

Wang Liangcai also breathed a sigh of relief quietly.

Wang Liangcai likes Yang Rui's way of speaking and doing things.

He likes Yang Rui to use "your group" or "your group" to describe. The usual habit of domestic scholars is "you group", the difference between the two is individualism or collectivism.

In the 1980s, individualism was undoubtedly condemned and oppressed by collectivism. If you change a person or a laboratory, the three words "your group" are enough to start a controversy.

However, Yang Rui can say whatever he wants, and those who accept it don't have to worry about the impact.

The three words "your group" carry Yang Rui's authoritative Yu Ze, so that Wang Liangcai, as a secondee, can also eat in the genetic engineering laboratory.

As for Yang Rui's way of doing things ~www.NovelMTL.com~, it has won the praise of researchers.

Everyone is so busy that there is no time to pass on the family, you still have a meeting or something, believe it or not, I will spray you on your face?

Wang Liangcai smiled and said again: "In terms of nuclear injection, we decided to learn from your previous technical experience, use pulses to penetrate the plasma membrane, and at the same time, use a transparent bag for fixation."

"That is to use a strong pulse." Yang Rui is very familiar with the details of the experiment. The related research on cloned sheep is really full of knowledge.

When Wang Liang saw that Yang Rui understood it, he was very excited and said "Yes" repeatedly, and then said: "We have done a lot of comparative experiments and finally determined the smallest intensity pulse that can break the plasma membrane..."

Yang Rui listened again.

Wang Liangcai was talking about a very small point, but a correct fulcrum is capable of lifting... at least blowing up an earth.

Using pulses to break the plasma membrane is a great change from the previous nucleus injection method. With this method, you will also encounter some problems, but if it is resolved, it is indeed a bright road.

"Professor Yang, what do you think?" Wang Liangcai asked softly, awakening Yang Rui from his contemplation.

"I still need to look at other people's repeated experiments, but Lao Xu, you can focus on the activation and in vitro culture of reconstructed embryos for public relations." Yang Rui said that it was tantamount to advancing the progress of the project.

Everyone in the laboratory cheered quietly.

Only Gu Qiang walked back to the backyard with some excitement, staring at the incense burner in front of the courtyard wall, silently in a daze.

I feel that the experiment is still very smooth, but why can't it be done by Wang Liangcai?

It’s not right. What I did before was smoother than Wang Liang. Which variable has changed? Has the result changed?

Gu Qiang stared at the front blankly, wishing to formulate a formula to solve this problem.