Rebirth of the God-level Xueba

"Sidenafil sells for US$7 in North America. After deducting the cost, we can get a gross profit of about five yuan per grain. This is mainly because Greenstone Point has taken on a lot of the cost in the early stage. They want to win Westland. The global sales agent of Nafei is willing to take on a little more..." Yang Rui held the report in his hand, and did not open it, but introduced it to Director Hu like a retelling.

Director Hu is the director of the Chemical Drug Promotion Office, and is considered to be a supervisory unit of Huarui.

Of course, Yang Rui can also report to the Food and Drug Administration of the Ministry of Health and other departments, but that is unnecessary and people are embarrassed to listen.

Director Hu listened very seriously.

What is going on with the new drug? Before Yang Rui, there was really no domestic experience.

Regardless of the number of drugs approved by the country each year, except for generic drugs, the rest are proprietary Chinese medicines. Proprietary Chinese medicines can only make money from the domestic market, and what they make is the most boring money.

In the 1960s and 1970s, the country still exported proprietary Chinese medicines to Southeast Asia, Hong Kong and Macau, but there were few after the 1980s. The main reason can be said to be the influence of many cultural factors, among which the influence of the FDA is inevitable.

Before the FDA, the quality of medicines in Europe and the United States was actually not very good. It was not common for people who died of food and people who were disabled. There were not many diseases that could be treated. Many common diseases were powerless, especially terminal illnesses like cancer. Taking western medicine and traditional Chinese medicine, the survival time is about the same, and it basically depends on personal physique and spirit.

However, after the 1980s, the level of western medicine in common diseases has obviously risen to a higher level. From the perspective of scientific research, it is a generation of scholars who grew up after World War II, especially those who grew up in the era of genetics. The biological technology studied has finally begun to be applied to the field of people's livelihood. For example, Dalbecco’s cancer conquering plan in the 1970s failed, but the US$1 billion was not a pure waste. The research results generated by this money were finally released in the 1980s and 1990s. Up.

With this kind of scientific research foundation, the strong politics of the West has room for development.

By about 90 years, Southeast Asian countries have established corresponding drug review mechanisms, and the traditional Chinese medicine gameplay is not easy to achieve.

For leaders like Hu Chi, he hates and fears words like FDA and Western medicine.

This feeling is a bit like Chinese football is facing the five major leagues and the World Cup. On the one hand, he is eager to enter the game. On the other hand, it is not himself that decides to enter the game. In addition to trying his best to understand the situation and issuing some useless commands, all that is left is to promote that football originated from Cuju. During the Great Song Dynasty, there were Cuju masters who used the ball to enter the road and reach the sky...

Sildenafil passed the FDA review, which is equivalent to a player entering the Premier League giants, selling well, it is equivalent to becoming famous, Hu Chi naturally wants to know the details.

He wanted to know, Yang Rui introduced.

He first talked about the review process of clinical phase three and clinical phase four, then later negotiations with Pfizer, then talked about the contract and sales policy of Greenstone Point, and then the performance of sildenafil in the market and the withdrawal Several modes of funding.

Hu Chi listened ignorantly.

The Chinese in the 1990s knew too little about foreign countries, even a pseudo-high-level person like Hu Chi, who did not know the professional situation in the field of medicine.

After listening for a while, Hu Chi finally gave up, decided to start with what he knew, and smiled: "In this way, you still earn it, hahahaha..."

"Earning is earning. Having said that, I want to talk about where the funds go." Yang Rui also stated his goal of this trip.

Hu Chi nodded again and again: "The funds have to be spent to be valuable, you say."

"The Ion Channel Laboratory of Peking University is ready to participate in the Genome Project. The equipment, equipment, personnel and training are all completed. Could you please come forward and urge negotiations." The Human Genome Project is an international cooperation, that is, between countries. Planning, so it is necessary to talk about the country as a unit. Of course, Yang Rui had done the preliminary communication a long time ago. There is not much professional part left, and the rest is political and diplomatic work.

However, politics and diplomacy are also the most complicated part. In the context of international cooperation and confrontation, no one knows whether they will become a bargaining chip for exchange.

The international situation in the 1990s was very unfriendly to China, and it was a far cry from the mid-1980s.

When Yang Rui received the Nobel Prize, he was praised by the media wherever he went. Inside the Nobel Prize Committee, there was even a voice hoping to give China a Nobel Prize to promote the development of China’s democratic cause from the side...

But after 90 years, the voice of the media has completely changed, and everything in China will become wrong.

Yang Rui’s cloned sheep is almost always regarded as a threat...

This is the political correctness of the Western world, and it is also what various committees care about most.

If it is not for the fact that the pharmaceutical company is really strong, the medical system is indeed rich, the lobbying group is indeed powerful, and the mouthpieces really need to use it, the passage of sildenafil will be subject to various restrictions.

Therefore, Yang Rui is not very casual about joining the Human Genome Project.

Hu Chi also knew the difficulty of this matter, and said in deep thought: "You also know the current diplomatic situation, I can only say that it is doing my best."

"En..." Yang Rui rubbed his chin and said, "If necessary, we at Peking University can provide some help, such as funding and personnel."

As far as his current influence is concerned, it is enough to represent Peking University.

As long as projects like the Human Genome Project are won, Peking University's influence will be greatly enhanced. This is a great thing that both sides look forward to.

Hu Chi didn't expect Yang Rui to say this, and couldn't help laughing: "As for sildenafil, they should also help."

"It's better to give something real." Yang Rui gave the money generously. Greenstone Point was engaged in lobbying in the United States and spent tens of millions of dollars, tens of thousands or even tens of thousands of dollars in cocktail parties, which consisted of seven or eight parties, enough for 800 running seats in the country, and returned home for three and a half years.

A unit like the Ministry of Foreign Affairs is very happy with its staff. Even if you don’t need any gray income, you can save a little bit of travel expenses and buy some foreign specialties. But for the unit itself, the cost of every business trip must be used. Foreign exchange, I really can't say that it is wealthy.

In fact, there are units such as the police station's criminal police team. Although the employees are moisturizing on weekdays, when it comes time to handle the case, it is not a small amount to drive thousands of miles to obtain evidence, and to spend a long time on board and lodging.

Yang Rui knows this, so he often donates money to the police department in his jurisdiction. In the same way, he doesn't care about donating money to the foreign affairs department.

If you don't count as a plug-in, if you analyze the difference between him and the scholars of his time, besides Yan Gao, he is mainly rich.

If you need to analyze it carefully, it is rich and generous.

Other domestic scholars, even if they get large sums of money, will mostly withhold money because of past experience. This is an era when everyone still regards thrift as a virtue.

Yang Rui doesn't have this habit. Scientific research has reached its peak, but it is actually krypton gold.

For any advanced skills, if you want to improve, you have to spend several times, tens of times, or even hundreds of times the money of the previous level.

In 1990, China was accustomed to doing follow-up research. Simply put, it was accustomed to chasing big bosses. He didn't have the consciousness of breaking into the world on his own. When spending money, he naturally liked to consider cost performance.

However, being server first has never been a cost-effective thing.

Although Hu Chi is not accustomed to such a straightforward operation, seeing Yang Rui insisted, he promised and turned around and said, "In this case, you have to consider the issue of domestic competition."

This is his intention to mention Yang Rui.

Yang Rui is no longer the first brother of the year. He smiled and asked, "Have you heard anything about it?"

"You know where I am now, there will always be someone who will come and test it." Hu Chi first explained, and then said: "Peach pickers are always indispensable."

"Do you think they can pick it?" Yang Rui asked slightly seriously.

Looking at the country, Yang Rui is not the only one calling for the Human Genome Project.

Regardless of how Yang Rui shouted the Human Genome Project from time to time, even at the Nobel Prize site, when the national team decided on the order, it was never judged according to the size and frequency of the sound.

People can mention the scholar who first called the Human Genome Project, or the oldest qualified scholar, or just bring a member of the academic department to take the lead, which is justified.

The Nobel Prize is only an award, not a qualification, it is the academic committee.

Moreover, the international reputation of Professor Cai, Wu Hongbo, and Academician Zhu cannot be compared with Yang Rui, but the domestic reputation is not weak at all.

At that time, the Human Genome Project will be established. It is not impossible to give Yang Rui a deputy team leader and then hang up the team leader.

Of course, Hu Chi supported Yang Rui, so he specifically reminded him, and said: "If you pay attention, there should be no problem, but you have to take it to heart."

Speaking of this, Hu Chi said: "You can attend more conferences recently, and I will remind everyone. In addition, you can also mention the Human Genome Project and get a preparation team."

Yang Rui said a little bored: "How can I have time to do so much useless..."

The preparatory team is all about lining up to eat Guoguo. Everyone is going to settle down. Everyone is happy, but they won't even come to grab it.

It is equivalent to a promise to everyone, and then keep one's own high position.

But Yang Rui is also reluctant to do this.

Seating is not as easy as he imagined, and it is not his expertise. The most important thing is that the Human Genome Project is really going to do things. When that happens, a group of old men in their seventies, who will work?

Hu Chi asked: "What do you have to do recently?"

Yang Rui broke his finger and said, "I'm going to class, and Huarui has to consider developing new drugs. Ion channel laboratory and Huarui laboratory are also doing regular research. In addition, I plan to build a medicine valley. ."

"Medicine Valley?"

"Concentrating some pharmaceutical-related companies is like a development zone, but it is done by Huarui private. It does not pursue short-term benefits, and there is no trouble in the development zone to take care of this and that. It is simply to concentrate industries and concentrate some companies. In addition, we only rent but not sell supporting housing for enterprises, reducing their worries about the future." Yang Rui paused and said: "The loan line given by the Bank of China is almost tens of billions, and it has to be used."

"Is it big?"

"Now it occupies a large area of ​​Pudong, and Shenzhen has also given a large piece of land. It can accommodate hundreds of companies, and there is still room." Yang Rui paused, and said lightly: "Building a factory is the enterprise itself. However, in order to attract pharmaceutical factories, we have to undertake a large number of housing constructions. It is currently estimated that at least 500,000 workers can be accommodated, plus the follow-up, that is, 1 million suites. The amount given by the Bank of China is just right."

Hu Chi's eyes jumped: "Don't you want to repay the loan?"

"Subsequent profits are still there. Besides, isn't there a rent? If the units are paid, it will save a lot of trouble."

"But... 1 million sets?"

"Build slowly, don't worry. The loan from Bank of China is not unconditional. They are also willing to invest in infrastructure construction. If they are all used to make new medicines and buy machinery and equipment, they will worry about it."

"This is the same, but your plan is really big."

Yang Rui laughed twice and said: "I originally mentioned an idea, but the governments of the two places were too active. They sold land at a low price, and they were subsidized by policies. There was no way to make trouble, and the more they got worse."

"Then you have to be careful, don't make up the gap when the time comes."

"The Bank of China's loan is issued in proportion to our US dollars, and the risk is not too great." Yang Rui chuckled, somewhat guilty.

How much will the 1 million suites in Shanghai @海和深@ Zhen be worth in 20 or even 30 years? Yang Rui didn't dare to count himself, he could only say that if Hua Rui wanted to develop new drugs in the future, the rent would be enough.

There are many state-owned enterprises that survive on rent, but they are not inferior to a private enterprise.

For Yang Rui, Yaogu is really to solve the current problems.

Bank of China’s loans must be spent, and should not be spent in places that are too risky. Otherwise, others will also have to interfere. In this case, infrastructure investment is the best choice. On the other hand, Huarui does need to have concentrated industrial bases in big cities. With the hot sale of sildenafil, Huarui’s sales network across the country has been greatly enhanced, and the brand has gradually become louder. At this time , We can't just look at the development of high-end new drugs.

With China's industrial scale and consumer market, once involved in the production of various generic drugs, the industrial park with hundreds of thousands of workers cannot really be ahead.

As for the 1 million houses, in this context, it is more to increase Yang Rui's personal satisfaction-knowing that the house is going to fly to the sky, it makes no sense to buy two more.

For this reason, Yang Rui also used the high-standard housing as an excuse ~www.NovelMTL.com~ to request that the house be built as large as possible.

Where did Hu Chi guess Yang Rui’s thoughts, he turned back to the previous topic and said, “Since you are going to be Medicine Valley, it’s better to be like this. In the name of the Chemical Medicine Promotion Office, I will change the GMP standards you got before. , It has been promulgated in advance."

"Promulgate now?"

"Policies and regulations are all prepared. If they are implemented on January 1 next year, the review can begin this year. This matter has always been promoted by you. It just so happens that you have to take time to understand the status of various pharmaceutical companies. You are ready to catch it. How about another committee from the existing GMP committee?" Hu Chi said it for granted, and expressed full respect for Yang Rui.

Yang Rui was surprised, but he saw the murderous aura.

The GMP standard mentioned by Hu Chi is a rigid standard for pharmaceutical companies. If it fails to pass, the result will be shut down and transfer.

As the designer of standards, Yang Rui is well aware of the difficulties of standards. Historically, there were more than 4,000 domestic pharmaceutical companies. In the end, there were more than 2,000 remaining, including those newly built later, which is equivalent to half of the pharmaceutical companies. , Facing the crisis of annexation or bankruptcy.

The committee responsible for standard review and its person in charge are tantamount to holding the power of life and death of all pharmaceutical companies across the country.

In this kind of full-scale review, even a prestigious company may be eliminated because of shortcomings in a certain area. Yang Rui looked at Hu Chi and did not speak for a while. Such a major decision must not be a shot. I suddenly thought of it when I pat my head.

Hu Chi deliberately pretended to laugh twice and said: "You are in charge of the GMP audit committee, and you immediately have the power to do what medicine valley is. No one dares to pick your peaches, right?"

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