Rebirth of the God-level Xueba

Arnold and Frankie lowered their heads to discuss, and employees from other companies also gathered around, discussing and calculating in a low voice.

After reading what she was holding, Grace looked up and saw that several people were talking in the corner. She couldn't help but curl her lips and said, "You are all evaluating clinical candidates. There is not much difference between the evaluations of each family, so why not read it out loud. , To save some time and let everyone devote their energy to real research."

Everyone is from a pharmaceutical company. You know what you’re doing with your chin. But the difference between a fig leaf and no fig leaf is still very big. It’s like your neighbor gave birth to a child, whether it’s a neighbor. Whether it’s yours or yours, you don’t have to say it—"Congratulations, the child is really yours" does not make neighbors happy.

It’s a pity that Grace is not a good neighbor. Regardless of the fact that other people are still looking at each other, she said to herself: "The results of the animal experiment on iron ketones are very good. Everyone can see what use your secret calculations are. Don't you know what you have done?"

"The results are indeed very good, but the side effects are also great. We were discussing the side effects just now." Arnold lied without opening his mouth.

Grace hummed and said: "It's just gastrointestinal reactions, joint pains, mild drug allergies, liver dysfunction, zinc deficiency, weight gain, dry skin, rash, agranulocytosis and neutrophil deficiency... What's great, these are just simple questions compared to the dangers faced by thalassemia patients."

Yang Rui stared at it, and reluctantly added: "These adverse reactions are relatively mild and reversible, and are related to the dose and individual sensitivity. The most serious complication is agranulocytosis, but the probability of occurrence is very low. Temporary."

"Nevertheless, does the fda and other institutions think so? There are so many problems with animal experiments, and it takes a long time to enter clinical trials." So far, no company has proposed an acquisition or purchase plan. , But at this stage, Arnold and others have already consciously lowered the expectations of deferiprone.

Business in the pharmaceutical field is very expensive, very expensive, and it is not easy to reduce anything at all. Arnold himself is the company's professional negotiator, and he will not let go of a word.

Grace sneered at Arnold's words and said: "Deferiprone can be used orally. This alone makes it a great improvement over deferoxamine. FDA will want to understand. If they still play golf... "

"Or the Yankees box, the same effect." The man sitting on the right said a word, followed by another: "The favorite of us Americans is always baseball, always baseball!"

"Because your football is so boring." Frankie used the word, in the UK, it is football, and in the United States, it is rugby, any English is upset with Americans, or any American is upset with When the British, they can all be used to provoke, try a hundred spirits.

The man on the right really felt the provocation, sneered, and said: "If I feel bored, I will find a woman, not a bastard."

"You're Raymond from Greenstone Point, right?" Yang Rui didn't want a few foreigners to quarrel in the conference room of Peking University, and stood in the middle to interrupt them.

"I'm Raymond, and you have a good memory." Raymond has a broad shoulders and a strong voice.

"Lv Shijiao is also an original drug company, I definitely remember." Yang Rui smiled and nodded. Compared with the well-known super pharmaceutical companies like Pfizer, Greenstone Point is only a medium-sized original drug company. Despite this, its annual sales are also more than 2 billion US dollars, and it is also a giant in other industries.

Yang Rui looked at both sides and said with a smile: "Everyone is here to learn about the animal experiment of desferiprone. Let's talk about animal experiment today. Other issues will be discussed later."

"The animal experiment is perfect. What's more to talk about." Grace folded her arms and looked at a group of men proudly, before she almost said her "Chihuahua Dog" evaluation.

"You do have very beautiful data, but we haven't got all the data." The Norwegian sitting on the far right looked up and said, but his eyes were aimed at Grace.

Grace's Nordic ancestry is very eye-catching, and it is incomparably in line with the Norwegian aesthetics. They say no, but in fact they prefer this kind of fashionable girl with a mix of Nordic and British and American styles.

Grace turned a blind eye to his eyes, and said, "I don't need all the data. The current results are enough for your evaluation."

Arnold coughed vigorously and was reluctant to talk about the evaluation again.

The representatives of other companies also remained silent, looking down at the experimental instructions Yang Rui gave them, quietly doing their own evaluations.

The meeting room suddenly fell silent.

Grace snorted dissatisfiedly, sat next to Yang Rui, and said boredly: "You should give me the enhanced version of the information now."

"It is impossible for me to take those materials out of the laboratory." Yang Rui said, "I will show it to you when I go back."

"Look at what they look like, you can't finish the analysis in an hour or two." Grace said, and then said: "You should find a good salesperson, otherwise, your deferiprone will not be sold at a good price."

"How do you know that I will sell iron ketone? I can do clinical trials myself."

"Are you ready for $200 million?" Grace glanced at Yang Rui like a fool.

The 200 million U.S. dollars in 1984 is not a small number, at least equivalent to 400 million U.S. dollars 30 years later. In fact, 30 years later, pharmaceutical companies often prepare more than 700 million U.S. dollars for a new drug. It's not that you have to spend so much money, but if you don't have so much money, the risk of suspension due to the money will greatly increase, and investors will lose confidence.

Yang Rui didn't have 700 million U.S. dollars, and he couldn't put out 200 million U.S. dollars. Therefore, if deferiprone wanted to go public, it could only be done through large companies.

Yang Rui chuckled and said something he didn't believe in: "We can list in other countries first."

“It’s just spending more money. Americans won’t reduce the number and cost of your clinical trials just because your medicine is on the market in other countries, nor will it in Europe. Only medicines that pass the fda can pass. Various agreements enter the European and Asian markets." Grace emphasized to Yang Rui that she didn't want a good medicine to fail to go on the market because of Yang Rui.

Yang Rui sighed. This is what makes American Dad so powerful. If you don't follow his standards, you will have to spend more money. This is more terrifying than the death penalty.

There are decapitating businesses in the world, but there is no loss-making business.

But from another point of view, although the bloated fda is inefficient, the safety of drugs that have passed fda is indeed commendable. Compared with the drug supervision bureaus of third world countries, fda is still much more reliable. .

"If Zelecom offers a price lower than US$20 million," Grace said: "Deferiprone should be able to sell at this price after completing animal experiments."

Yang Rui smirked, not discussing the issue of price.

Grace thought he didn’t want to sell it, and added: “You can sell this drug to a large pharmaceutical company as soon as possible, so that patients suffering from thalassemia can get life-saving drugs. The money earned, if you want, I I suggest you set up a non-profit charitable fund. Of course, you can continue to invest in laboratory research."

"At that time, you have to leave." Yang Rui asked.

Grace nodded naturally, and said: "Although I plan to stay in China for five years~www.NovelMTL.com~, the progress of deferiprone has exceeded the expected progress, so I have no reason to stay. The time saved, I am going to use it. With regard to the promotion of desferiprone, I also plan to raise a portion of funds to fund thalassemia patients who cannot afford the treatment."

"Very ideal."

"Thank you." When Grace was studying, she established the idea of ​​working for a lifetime in a non-profit organization. After graduating from her Ph.D., she rejected a number of high-paying jobs, traveling to and from Africa and other places, doing things that few pharmaceutical companies paid attention to. The research on genetic diseases has finally established the research direction of metal chelating agents, which are difficult to make money.

If you are looking for a reasonable analysis, Grace may have too much "white guilt", working in Africa, helping poor African families, alleviating the suffering of African children due to genetic diseases, and making Grace feel Easier.

Yang Rui didn’t comment on this. After the representatives of Zelican and other companies read the documents, they almost read, and said: “The animal experiment on deferiprone in the Huarui Laboratory is nearing completion. We welcome representatives from each company to come to the company to learn more about it. In case, each company is limited to two people. Those who are interested can fill in the application later."

"Give me an application."

"We want too."

"It's all done." Arnold chuckled and said, "Zelikon is not afraid of competition."

Yang Rui nodded and asked people to send applications.

Arnold said in a low voice to Frank: "Check the status of their patent applications."

...