my black technology library

Falling in love with you, my black technology library

Xingyao Experimental Center, biological experiment area.

Professor Wei Zhihan led his scientific research team to conduct in-depth research on the genetic enhancement project.

Jiang Ming is a researcher of one of the sub-projects of the Human Gene Enhancement Project. As usual, he drove the flying car into the experimental area, and arrived at the laboratory after passing a series of security tests.

"Good morning! Mr. Chen, Sister Lin!" Jiang Ming changed into his lab uniform and greeted his colleagues Chen Kai and Lin Meifeng with a smile.

"Morning? Don't you check the time! It's almost noon now." Lin Meifeng teased with a smile.

"That's right, Xiao Lin and I have been busy all morning, but you came late. As usual, you will arrange next week's activities." Chen Kai looked at Jiang Ming and signaled.

"Brother Chen, I was busy until 2 o'clock in the morning last night. I didn't miss the progress of the work I just did." Jiang Ming smiled and explained quickly.

"You kid stayed up late and worked overtime again. Next time, I will file a complaint with Director Sun." Lin Meifeng gave Jiang Ming a look and reminded.

In order to prevent scientific researchers from working for a long time and ignoring their physical health, the experimental center has customized reasonable work and rest regulations. However, many scientific researchers still ignore these regulations. thing.

"Sister Lin, don't threaten me. I had special circumstances last night, so I had to stay up late and work overtime. This is in line with the regulations of our department." Jiang Ming explained with a smile.

"What's the special situation? Did you make a breakthrough in your research last night?" Chen Kai turned to look at Jiang Ming and asked with concern.

Lin Meifeng stopped what she was doing and looked at Jiang Ming.

Jiang Ming nodded with a smile, and turned on the virtual screen of the console: "Brother Chen, Sister Lin, come and take a look at my work results last night! If there is no accident, the scientific research work of our group should be completed! "

Hearing this, Chen Kai and Lin Meifeng stepped forward one after another.

All I saw was a three-dimensional image of an intestinal tube appearing on the virtual screen, with various data marked around it, which was the result of the experimental data of a small white mouse's original intestinal tube.

In mammalian embryonic development, the gastruula is the precursor of many important organs, including the intestine, stomach, pancreas, liver, lung, esophagus, pharynx and thyroid. Therefore, the development and differentiation of the gastruula has always been the focus of embryonic development research.

Unlike mesoderm cells, which will develop into mesenchymal cells, endoderm cells, which exist as a single layer of cells within the gastrula tube, will form functional epithelial cells in various organs, such as absorptive cells in the intestine, acid-secreting cells in the stomach parietal cells, and exocrine cells in the pancreas.During the stage of organogenesis in mice at 9.5-13.5 days of gestational age, the intestinal tract gradually begins to emerge with morphologically characteristic organ precursors.

This process is dominated by mesoderm cells, while endoderm remains a monolayer at this stage.

Jiang Ming and his group are mainly responsible for experimentally verifying the influence of abnormal expression of key enhancer gene factors on organ differentiation and cell lineage fate determination in mouse models.

The gene enhancement project has been going on for more than half a year, and many scientific research results have been obtained during this period. However, there is still a long way to go before the completion of human gene enhancement. Currently, it is in the animal experiment of using mice to achieve gene enhancement.

All the biochemical experiments are located in the laboratory of the moon base, and Jiang Ming and the others have realized ultra-distance experimental connection through the virtual network.

Last night, Jiang Ming had a brainstorm and thought of a new idea, so he conducted a remote experiment according to his idea. The experimental results showed that the seemingly identical endoderm cells showed different gene expression patterns along the anterior-posterior axis, even in the development of the intestine. Some organ-specific genes are expressed at the earliest stage.

Soon, both Chen Kai and Lin Meifeng discovered the unusualness of the experimental data.

"You, how did you do it?" Chen Kai suddenly turned his head, looked at Jiang Ming in surprise and asked.

"I found that knocking out key transcription factors directly shifted cell lineages, for example, knocking out sox2 shifted the chromatin epigenomic state of gastric epithelial cells to the chromatin state of neighboring organs; knocking out cdx2 made The chromatin state of intestinal epithelial cells changes to the chromatin state of the foregut,...so I tried it in this direction." Jiang Ming explained with a smile,

After a pause, Jiang Ming went on to introduce: "So, I conducted an experiment on sox2 and cdx2, two transcription factors that are critical to the maturation and differentiation of intestinal epithelial cells, by comparing the chromatin after knockout of sox2 or cdx2 gene Compared with the changes in the control group, combined with the unique chromatin accessibility patterns of different organs,..., as a result, hey, I found the key gene."

"Great! According to this experimental direction, our project has finally made a breakthrough." Lin Meifeng said happily.

"Yes! The experimental results confirmed the activity of organ-specific gene transcription activities, based on high-throughput sequencing technology for determining chromatin accessibility at the genome-wide level, and can identify potential regulatory regions and transcription within the genome Factor binding sites, ..., the chromatin state and transcription factors involved in the regulation of gene expression during intestinal tube development, this set of experimental data is too precious." Chen Kai nodded excitedly, highly agreeing with Jiang Ming's experimental results .

"Have you reported the results of the experiment?" Lin Meifeng looked at Jiang Ming and asked with concern.

"Not yet! It was too late last night, and I am going to submit the results of this project today. Brother Chen, Sister Lin, can you help me!" Jiang Ming looked at Chen Kai with a smile, and Lin Meifeng suggested.

Hearing this, Chen Kai and Lin Meifeng lifted their spirits together.

"Xiao Jiang, this is the result of your experiment. It's inappropriate for us to participate now!" Chen Kai said shyly.

"Yes! This research result is your discovery..." Lin Meifeng nodded in agreement.

"What are you talking about? We did this project together. Without your hard-earned scientific research results in the early stage, how could I have my breakthrough today? We did this scientific research project together, and the results are of course shared together! Besides, our center is not There is a scientific research achievement sharing system! Just follow the system process!" Jiang Ming explained with a smile.

Hearing this, Chen Kai and Lin Meifeng nodded happily, they were no longer entangled.

"Okay, let's do the finishing work, you should quickly write the project completion form!" Chen Kai said decisively.

Jiang Ming nodded and started to get busy.

Soon, the three of them enthusiastically devoted themselves to the finishing work of the scientific research project.

In the Xingyao Experimental Center, there are hundreds of thousands of scientific research groups like Jiang Ming, Chen Kai, and Lin Meifeng. Even a single person can set up a scientific research project team to undertake the scientific research tasks of the experimental center.

According to the difficulty of scientific research tasks, members of the scientific research team have the same major or different majors, and gather the intelligence of the group to overcome those complicated scientific research tasks together.

For just one gene enhancement research project, there are hundreds of scientific research groups working together to carry out scientific research work on this large scientific research project.

Soon, Jiang Ming wrote the completion form of the scientific research project, uploaded the report to the human gene enhancement project team through the scientific research intelligent auxiliary system, and was immediately conveyed by the scientific research auxiliary system to the relevant person in charge of the project team-Professor Wei Hanzhi, and several other core members project member.

Biological gene research area, large meeting room.

Professor Wei Hanzhi and a group of scientific research members are conducting a scientific research meeting to discuss the scientific research results that have been successfully overcome every day, and bring together the research results of all scientific research groups to promote the scientific research progress of the entire scientific research project.

"Professor Wei, Professor Wei, take a look at the chromatin epigenetics project. The research of the No. 172 group has made a breakthrough, and the research results on the potential expression of alienation genes have come out."

The seminar was going on, and suddenly a participant exclaimed loudly, his voice seemed extraordinarily excited.

"Wow! The research results really come out!"

"This breakthrough is too critical, Professor Wei, let's start the human cell experiment!"

"The research on the alienation performance of the key factors of the genetic code has been completed, and the risk of the experiment has been greatly reduced."

"Yes! It's time to carry out the fusion experiment of human genes."

……

After confirming the news, all the scientific researchers looked at Professor Wei Hanzhi excitedly and proposed to him.

"Okay! Let me confirm with President Li. If there is no problem, we will start the next step of the experiment process." Professor Wei Hanzhi responded happily with a face full of joy.

After finishing speaking, Professor Wei Hanzhi looked at Liu Chengfeng who was sitting on his right, and ordered: "Old Liu, everyone has worked hard during this period, confirm the scientific research results as soon as possible, and arrange the scientific research bonus as soon as possible."

"Well! I will hurry up and make arrangements." Liu Chengfeng readily complied.

In the afternoon, after Professor Wei Hanzhi had a phone call with Li Yi, the entire genetic enhancement project was pushed forward quickly.

However, all of this has nothing to do with Jiang Ming, Chen Kai, and Lin Meifeng. After submitting their scientific research results, their scientific research work has come to an end. After being busy for more than half a year, they finally have time to start their vacation.

Jiang Ming drove a new flying car - Night Elf II, at a speed close to the speed of sound, and drove swiftly on the high-speed highway in the sky. He had a panoramic view of the magnificent city scenery of Xingyao City.

"Boom..." The stereo in the car suddenly sounded a call reminder.

"Wade, turn on the autopilot mode and connect to the call." Jiang Ming gestured quickly.

"Okay, boss!" A little boy's head appeared on the virtual screen in the car, and the next moment, the steering wheel in the car shrank.

Immediately afterwards, a larger virtual screen appeared, and a full-body image of a girl with a round face appeared, which was his girlfriend-Zhang Yingying.

"Aren't you in the lab? Where are you!" Zhang Yingying asked as soon as the video call was connected.

"Going for a drive! The Shadow Prince who just got it doesn't have time to drive it out to play. I plan to go shopping for a while and pick you up around the same time." Jiang Ming explained with a smile.

After a pause, Jiang Ming looked at his girlfriend and suggested: "The scientific research project is over, I have time to accompany you now, don't you want to travel around the world! Why don't you take this opportunity to realize this idea?"

Hearing this, Zhang Yingying's heart skipped a beat, but when she thought that she still had work to do and couldn't spare so much time, she immediately felt discouraged.

"What? Can't you go?" Seeing his girlfriend's dejected expression, Jiang Ming asked unexpectedly.

"That's right! I'm so busy with work, so I can take a long vacation!" Zhang Yingying sighed.

"Why don't you quit your job!" Jiang Ming suggested.

Zhang Yingying turned over the silver: "What will I eat after quitting, drink the northwest wind!"

"I quit my job, and I will support you! There is a lot of funds left for this scientific research project, and with a considerable scientific research bonus, it should not be a problem to support you." Jiang Ming smiled and introduced confidently.

"Raise me? Are you proposing to me?" Zhang Yingying blinked and asked with a smile.

Jiang Ming lifted his spirits, and confirmed with a smile: "Yes! Mrs. Jiang, let's treat this global tour as our honeymoon, okay?"

"Propose to me on the phone, Jiang Ming, you idiot, do you want to die!" Zhang Yingying's complexion changed, and she asked angrily.

After speaking, Zhang Yingying angrily hung up the video call.

……

Jiang Ming was taken aback for a moment, then remembered something, and immediately realized that he had lost his composure.

"Wade, help me set a table at Dizhuang, and help me prepare a bouquet and a wedding finger for me to propose to my girlfriend." Jiang Ming quickly took remedial measures and ordered Wade.

"Understood, Boss, is it okay to reserve a seat at the viewing area, and there is also a proposal ring, please choose the style." There was a synthetic electronic sound in the car.

Soon, the virtual screen changed, and there appeared a dining table in front of the large French windows overlooking the night view of the entire Xingyao City, as well as more than a dozen wedding rings at different prices for Jiang Ming to choose from.

"Well, the location is fine, let's choose the fifth ring!" Jiang Ming confirmed the choice of the dining table, and chose a good-looking wedding ring at a moderate price.

"Okay, Boss, what do you want for dinner? Do you want to make a reservation according to Ms. Zhang's preference?" Wade continued to remind.

"Yes, it can be decided according to her appetite. Also, if you propose marriage, does Dizhuang provide any services?" Jiang Ming quickly confirmed.

"Yes, they provide twelve atmosphere group services for marriage proposals." Wade responded happily, and the next moment, twelve additional service options appeared on the screen.

Jiang Ming carefully previewed it. The price range is different, and the content of the service provided is also different. There are professional dance performances, various atmosphere enhancement sessions, playing videos, photos, ..., etc., which are very professional.

It's a pity that it has been revealed in advance, and there is no remedial measure now, otherwise, Yingying will definitely be moved so much that he will not marry.

"Just this one! Is there time to arrange it for the evening?" Jiang Ming chose a nostalgic version and asked.

"Yes, Boss, this one will provide businesses with videos and group photos of you and Ms. Zhang." Wade gestured.

"Well! Select some meaningful and good-looking ones from my data space, and send them to them!" Jiang Ming nodded and ordered.

"Okay, boss, the arrangements have been made. The total consumption is 32.7. If there is no problem, please enter the payment password." Smart assistant - Wade responded.

Jiang Ming nodded, operated on the virtual screen, and the payment was successful.